![]() ![]() After 20 months of using this drug, she reported having only 2-3 nocturnal. Marijuana was given the status of a schedule 1 drug class in the U.S. PubMed was used to retrieve all published studies and articles which evaluated the use of cannabis in epilepsy. © 2014 International League Against Epilepsy. There is also evidence it was used in medieval times to treat: nausea. The Division of Cannabis Control must establish rules for packaging and product standards, licensing and more. Much more needs to be learned about the mechanisms of antiepileptic activity of the phytocannabinoids and other constituents of Cannabis sativa.ĬBD Cannabidiol Charlotte's Web Dravet syndrome Medically refractory epilepsy THC. Two compounds found in the drug, THC and CBD, may have medical benefits. We briefly review some of the history, preclinical and clinical data, and controversies surrounding the use of medical marijuana for the treatment of epilepsy, and make a case that the desire to isolate and treat with pharmaceutical grade compounds from cannabis (specifically CBD) may be inferior to therapy with whole plant extracts. Some people who suffer from epilepsy believe that marijuana stops their seizures. ![]() This effect has persisted for the last 20 months, and Charlotte has been successfully weaned from her other antiepileptic drugs. ![]() This extract, slowly titrated over weeks and given in conjunction with her existing antiepileptic drug regimen, reduced Charlotte's seizure frequency from nearly 50 convulsive seizures per day to now 2-3 nocturnal convulsions per month. Through exhaustive personal research and assistance from a Colorado-based medical marijuana group (Realm of Caring), Charlotte's mother started adjunctive therapy with a high concentration cannabidiol/Δ(9) -tetrahydrocannabinol (CBD:THC) strain of cannabis, now known as Charlotte's Web. Charlotte, a little girl with SCN1A-confirmed Dravet syndrome, was recently featured in a special that aired on CNN. ![]()
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